TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - England KW - Female KW - Heroin Dependence/drug therapy KW - Humans KW - Male KW - Middle Aged KW - Opiate Substitution Treatment/methods KW - Prospective Studies KW - Time Factors KW - Treatment Outcome KW - Young Adult KW - Developmental trajectory KW - National KW - opioid use disorder KW - Treatment Effectiveness AU - B. Eastwood AU - J. Strang AU - J. Marsden A1 - AD - King's College London, Addictions Department, Box 48, Institute of Psychiatry, Psychology and Neuroscience, DeCrespigny Park, Denmark Hill, London, SE5 8AF, United Kingdom; Alcohol, Drugs, Tobacco and Justice Division, Health Improvement Directorate, Public Health England, 7th Floor, Wellington House, 133-155 Waterloo Road, London, SE1 8UG, United Kingdom. Electronic address: Brian.Eastwood@phe.gov.uk.; King's College London, Addictions Department, Box 48, Institute of Psychiatry, Psychology and Neuroscience, DeCrespigny Park, Denmark Hill, London, SE5 8AF, United Kingdom. Electronic address: john.strang@kcl.ac.uk.; King's College London, Addictions Department, Box 48, Institute of Psychiatry, Psychology and Neuroscience, DeCrespigny Park, Denmark Hill, London, SE5 8AF, United Kingdom; Alcohol, Drugs, Tobacco and Justice Division, Health Improvement Directorate, Public Health England, 7th Floor, Wellington House, 133-155 Waterloo Road, London, SE1 8UG, United Kingdom. Electronic address: john.marsden@kcl.ac.uk. BT - Drug and alcohol dependence C5 - Opioids & Substance Use CY - Ireland JF - Drug and alcohol dependence M1 - Journal Article PB - . Published by Elsevier B.V PP - Ireland PY - 2018 SN - 1879-0046; 0376-8716 SP - 200 EP - 208 EP - T1 - Continuous opioid substitution treatment over five years: Heroin use trajectories and outcomes T2 - Drug and alcohol dependence TI - Continuous opioid substitution treatment over five years: Heroin use trajectories and outcomes U1 - Opioids & Substance Use U2 - 29778774 VL - 188 VO - 1879-0046; 0376-8716 Y1 - 2018 Y2 - Jul 1 ER -