TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Analgesics, Opioid/agonists KW - Anxiety/complications/psychology KW - Employment KW - Female KW - Health Status KW - Humans KW - Lebanon KW - Male KW - Middle Aged KW - Needle Sharing KW - Opiate Substitution Treatment KW - Opioid-Related Disorders/drug therapy/psychology KW - Psychosocial Support Systems KW - Quality of Life KW - Risk-Taking KW - Young Adult KW - buprenorphine KW - Harm Reduction KW - Opiate-related disorders AU - A. Ghaddar AU - Z. Abbas AU - R. Haddad A1 - AB - BACKGROUND: Opioid agonist therapy has been widely used to reduce harms among individuals with opioid use disorder but its effectiveness has not been evaluated in the Middle East North African (MENA) region. This study aims to evaluate the effectiveness of a program using opioid agonist therapy in combination with psychosocial support on improving psychological and social well-being, reducing arrest, and reducing risky behavior in individuals with opioid use disorder in Lebanon. METHODS: A one-group pre-test post-test design study was performed at SKOUN Lebanese Addiction Centre between January 2013 and December 2014. Eighty-six out of 181 patients agreed to participate and completed the 3-month assessment and 38 concluded the 12-month assessment. Psychological (depression and anxiety, quality of life), substance dependence/abuse, behavioral (injecting behavior, sharing needles and paraphernalia), and social outcomes were evaluated at baseline, 3, and 12 months post-treatment. RESULTS: Remarkable statistical significance improvements were observed 3 months after treatment in most outcome variables including quality of life, anxiety, substance dependence, overdose, employment, and injecting behavior. Improvements were sustained 12 months after treatment. CONCLUSION: Results support expanding the access to opioid agonist therapy in other MENA countries to treat substance dependence and reduce harms among individuals with opioid use disorder. AD - Department of Biomedical Sciences, Lebanese International University, Beirut, Lebanon. ali.ghaddar@liu.edu.lb.; Observatory of Public Policies and Health, Beirut, Lebanon. ali.ghaddar@liu.edu.lb.; School of Pharmacy, Lebanese International University, Beirut, Lebanon.; Department of Narcotics, Ministry of Public Health, Beirut, Lebanon.; Department of Psychiatry, Lebanese University, Beirut, Lebanon.; Department of Psychiatry, Saint Joseph University, Beirut, Lebanon. BT - Harm reduction journal C5 - Opioids & Substance Use CP - 1 CY - England DO - 10.1186/s12954-017-0204-8 IS - 1 JF - Harm reduction journal M1 - Journal Article N2 - BACKGROUND: Opioid agonist therapy has been widely used to reduce harms among individuals with opioid use disorder but its effectiveness has not been evaluated in the Middle East North African (MENA) region. This study aims to evaluate the effectiveness of a program using opioid agonist therapy in combination with psychosocial support on improving psychological and social well-being, reducing arrest, and reducing risky behavior in individuals with opioid use disorder in Lebanon. METHODS: A one-group pre-test post-test design study was performed at SKOUN Lebanese Addiction Centre between January 2013 and December 2014. Eighty-six out of 181 patients agreed to participate and completed the 3-month assessment and 38 concluded the 12-month assessment. Psychological (depression and anxiety, quality of life), substance dependence/abuse, behavioral (injecting behavior, sharing needles and paraphernalia), and social outcomes were evaluated at baseline, 3, and 12 months post-treatment. RESULTS: Remarkable statistical significance improvements were observed 3 months after treatment in most outcome variables including quality of life, anxiety, substance dependence, overdose, employment, and injecting behavior. Improvements were sustained 12 months after treatment. CONCLUSION: Results support expanding the access to opioid agonist therapy in other MENA countries to treat substance dependence and reduce harms among individuals with opioid use disorder. PP - England PY - 2017 SN - 1477-7517; 1477-7517 SP - 017 EP - 8 EP - 78+ T1 - Opiate agonist treatment to improve health of individuals with opioid use disorder in Lebanon T2 - Harm reduction journal TI - Opiate agonist treatment to improve health of individuals with opioid use disorder in Lebanon U1 - Opioids & Substance Use U2 - 29216892 U3 - 10.1186/s12954-017-0204-8 VL - 14 VO - 1477-7517; 1477-7517 Y1 - 2017 Y2 - Dec 8 ER -