TY - JOUR
KW - Adult
KW - Female
KW - Health Services Research
KW - Humans
KW - Male
KW - Mental Disorders/psychology/therapy
KW - Mental Health Services/standards
KW - Middle Aged
KW - Outcome Assessment (Health Care)/methods
KW - Patient reported outcome measures
KW - Psychiatric Status Rating Scales
KW - Psychometrics
KW - Quality of Life/psychology
KW - Reproducibility of Results
KW - Capabilities
KW - Community treatment orders
KW - Mental Health
KW - Outcome measurement
KW - Psychiatry
KW - psychometric validation
KW - psychosis
AU - F. Vergunst
AU - C. Jenkinson
AU - T. Burns
AU - P. Anand
AU - A. Gray
AU - J. Rugkasa
AU - J. Simon
A1 - 
AB - BACKGROUND: Patient reported outcome measures (PROMs) are widely used in mental healthcare research for quality of life assessment but most fail to capture the breadth of health and non-health domains that can be impacted. We report the psychometric validation of a novel, multi-dimensional instrument based on Amartya Sen's capability approach intended for use as an outcome measure in mental health research. METHODS: The Oxford Capabilities Questionnaire for Mental Health (OxCAP-MH) is a 16-item self-complete capability measure that covers multiple domains of functioning and welfare. Data for validation of the instrument were collected through a national randomised controlled trial of community treatment orders for patients with psychosis. Complete OxCAP-MH data were available for 172 participants. Internal consistency was established with Cronbach's alpha; an interclass correlation coefficient was used to assess test-retest reliability in a sub-sample (N = 50) tested one week apart. Construct validity was established by comparing OxCAP-MH total scores with established instruments of illness severity and functioning: EuroQol (EQ-5D), Brief Psychiatric Rating Scale (BPRS), Global Assessment of Functioning (GAF) and Objective Social Outcomes Index (SIX). Sensitivity was established by calculating standard error of measurement using distributional methods. RESULTS: The OxCAP-MH showed good internal consistency (Cronbach's alpha 0.79) and test-retest reliability (ICC = 0.86). Convergent validity was evidenced by strong correlations with the EQ-5D (VAS 0.52, p < .001) (Utility 0.45, p < .001), and divergent validity through more modest associations with the BPRS (-0.41, p < .001), GAF (0.24, p < .001) and SIX (0.12, p = ns). A change of 9.2 points on a 0-100 scale was found to be meaningful on statistical grounds. CONCLUSIONS: The OxCAP-MH has demonstrable reliability and construct validity and represents a promising multi-dimensional alternative to existing patient-reported outcome measures for quality of life used in mental health research.
AD - Research Unit on Children's Psychosocial Maladjustment, University of Montreal, Ste Justine Hospital, 3175 Chemin de la Cote Ste-Catherine, Montreal, H3T 1C5, Canada.; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK.; Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Old Road Campus, Oxford, OX3 7LF, UK.; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK.; Faculty of Arts and Social Sciences, The Open University, Milton Keynes, MK7 6AA, UK.; Centre for Philosophy of Natural and Social Sciences, London School of Economics, London, WC2A 2AE, UK.; Department of Social Policy and Intervention, University of Oxford, 32 -37 Wellington Square, Oxford, OX1 2ER, UK.; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Old Road Campus, Oxford, OX3 7LF, UK.; Health Services Research Unit, Akershus University Hospital, 1478, Lorenskog, Norway.; Centre for Care Research, University College of Southeast Norway, 3900, Porsgrunn, Norway.; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK. judit.simon@meduniwien.ac.at.; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Old Road Campus, Oxford, OX3 7LF, UK. judit.simon@meduniwien.ac.at.; Department of Health Economics, Center for Public Health, Medical University of Vienna, Kinderspitalgasse 15, 1090, Vienna, Austria. judit.simon@meduniwien.ac.at.
BT - Health and quality of life outcomes
C5 - Measures
CP - 1
CY - England
DO - 10.1186/s12955-017-0825-3
IS - 1
JF - Health and quality of life outcomes
M1 - Journal Article
N2 - BACKGROUND: Patient reported outcome measures (PROMs) are widely used in mental healthcare research for quality of life assessment but most fail to capture the breadth of health and non-health domains that can be impacted. We report the psychometric validation of a novel, multi-dimensional instrument based on Amartya Sen's capability approach intended for use as an outcome measure in mental health research. METHODS: The Oxford Capabilities Questionnaire for Mental Health (OxCAP-MH) is a 16-item self-complete capability measure that covers multiple domains of functioning and welfare. Data for validation of the instrument were collected through a national randomised controlled trial of community treatment orders for patients with psychosis. Complete OxCAP-MH data were available for 172 participants. Internal consistency was established with Cronbach's alpha; an interclass correlation coefficient was used to assess test-retest reliability in a sub-sample (N = 50) tested one week apart. Construct validity was established by comparing OxCAP-MH total scores with established instruments of illness severity and functioning: EuroQol (EQ-5D), Brief Psychiatric Rating Scale (BPRS), Global Assessment of Functioning (GAF) and Objective Social Outcomes Index (SIX). Sensitivity was established by calculating standard error of measurement using distributional methods. RESULTS: The OxCAP-MH showed good internal consistency (Cronbach's alpha 0.79) and test-retest reliability (ICC = 0.86). Convergent validity was evidenced by strong correlations with the EQ-5D (VAS 0.52, p < .001) (Utility 0.45, p < .001), and divergent validity through more modest associations with the BPRS (-0.41, p < .001), GAF (0.24, p < .001) and SIX (0.12, p = ns). A change of 9.2 points on a 0-100 scale was found to be meaningful on statistical grounds. CONCLUSIONS: The OxCAP-MH has demonstrable reliability and construct validity and represents a promising multi-dimensional alternative to existing patient-reported outcome measures for quality of life used in mental health research.
PP - England
PY - 2017
SN - 1477-7525; 1477-7525
SP - 017
EP - 3
EP - 250+
T1 - Psychometric validation of a multi-dimensional capability instrument for outcome measurement in mental health research (OxCAP-MH)
T2 - Health and quality of life outcomes
TI - Psychometric validation of a multi-dimensional capability instrument for outcome measurement in mental health research (OxCAP-MH)
U1 - Measures
U2 - 29282075
U3 - 10.1186/s12955-017-0825-3
VL - 15
VO - 1477-7525; 1477-7525
Y1 - 2017
Y2 - Dec 28
ER -