TY - JOUR
KW - Adult
KW - Analgesics, Opioid/therapeutic use
KW - Comorbidity
KW - Depression/epidemiology
KW - Erectile Dysfunction/epidemiology
KW - Humans
KW - Malaysia/epidemiology
KW - Male
KW - Methadone/therapeutic use
KW - Middle Aged
KW - Opiate Substitution Treatment/statistics & numerical data
KW - Opioid-Related Disorders/drug therapy/epidemiology
KW - Quality of Life
KW - Risk Factors
KW - Severity of Illness Index
AU - J. B. Teoh
AU - A. Yee
AU - M. Danaee
AU - C. G. Ng
AU - A. H. Sulaiman
A1 - 
AB - OBJECTIVES: Erectile dysfunction (ED) is a problem commonly encountered by patients on methadone maintenance therapy (MMT). This study aimed to assess the prevalence of ED among this group of patients along with its risk factors and association with quality of life (QOL). METHODS: Male patients on MMT in a tertiary hospital in Malaysia were included in the study. A total of 134 patients with sexual partners were assessed for ED using the International Index of Erectile Function. Patients were assessed for substance use using Opiate Treatment Index (OTI) and depression using the Malay version of the self-rated Montgomery-Asberg Depression Rating Scale (MADRS-BM). QOL was evaluated using World Health Organisation Quality of Life (WHOQOL)-BREF. RESULTS: The prevalence of ED among patients on MMT was 67%, with 26.1% having mild ED, 30.4% having mild-to-moderate ED, 7.0% having moderate ED, and 17.2% having severe ED. Patients with depression were 4 times more likely to have ED compared with patients without depression, whereas increasing age significantly correlated with the severity of ED. Having ED predicted a poorer QOL in the social relationships domain. CONCLUSION: Depression is highly associated with ED, which negatively influences the social aspect of QOL among patients on methadone maintenance therapy.
AD - Department of Psychological Medicine, Faculty of Medicine (JBFT, CGN, AHBS); University Malaya Centre for Addiction Sciences (AY); and Unit for the Enhancement of Academic Performance (MD), University of Malaya, Kuala Lumpur, Malaysia.
BT - Journal of addiction medicine
C5 - Opioids & Substance Use
CP - 1
CY - United States
DO - 10.1097/ADM.0000000000000267
IS - 1
JF - Journal of addiction medicine
M1 - Journal Article
N2 - OBJECTIVES: Erectile dysfunction (ED) is a problem commonly encountered by patients on methadone maintenance therapy (MMT). This study aimed to assess the prevalence of ED among this group of patients along with its risk factors and association with quality of life (QOL). METHODS: Male patients on MMT in a tertiary hospital in Malaysia were included in the study. A total of 134 patients with sexual partners were assessed for ED using the International Index of Erectile Function. Patients were assessed for substance use using Opiate Treatment Index (OTI) and depression using the Malay version of the self-rated Montgomery-Asberg Depression Rating Scale (MADRS-BM). QOL was evaluated using World Health Organisation Quality of Life (WHOQOL)-BREF. RESULTS: The prevalence of ED among patients on MMT was 67%, with 26.1% having mild ED, 30.4% having mild-to-moderate ED, 7.0% having moderate ED, and 17.2% having severe ED. Patients with depression were 4 times more likely to have ED compared with patients without depression, whereas increasing age significantly correlated with the severity of ED. Having ED predicted a poorer QOL in the social relationships domain. CONCLUSION: Depression is highly associated with ED, which negatively influences the social aspect of QOL among patients on methadone maintenance therapy.
PP - United States
PY - 2017
SN - 1935-3227; 1932-0620
SP - 40
EP - 46
EP - 
T1 - Erectile Dysfunction Among Patients on Methadone Maintenance Therapy and Its Association With Quality of Life
T2 - Journal of addiction medicine
TI - Erectile Dysfunction Among Patients on Methadone Maintenance Therapy and Its Association With Quality of Life
U1 - Opioids & Substance Use
U2 - 27753719
U3 - 10.1097/ADM.0000000000000267
VL - 11
VO - 1935-3227; 1932-0620
Y1 - 2017
Y2 - Jan/Feb
ER -