TY - JOUR
KW - Adult
KW - Aged
KW - Analgesics, Opioid/therapeutic use
KW - Cross-Sectional Studies
KW - Female
KW - Humans
KW - Malaysia
KW - Male
KW - Methadone/therapeutic use
KW - Middle Aged
KW - Opiate Substitution Treatment/statistics & numerical data
KW - Opioid-Related Disorders/drug therapy
KW - Outcome Assessment (Health Care)/statistics & numerical data
KW - Treatment Outcome
KW - Young Adult
KW - effectiveness
KW - methadone treatment
KW - outcome study
KW - Quality of Life
AU - N. Ali
AU - S. A. Aziz
AU - S. Nordin
AU - N. C. Mi
AU - N. Abdullah
AU - V. Paranthaman
AU - M. Mahmud
AU - A. Yee
AU - M. Danaee
A1 - 
AB - BACKGROUND: Opioid misuse and dependence is a global issue with a huge negative impact. In Malaysia, heroin is still the main illicit drug used, and methadone maintenance treatment (MMT) has been used since 2005. OBJECTIVE: To evaluate the effectiveness of MMT. METHODS: This was a cross-sectional study conducted in 103 treatment centers between October and December 2014 using a set of standard questionnaires. Data were analyzed using SPSS Statistics 20. RESULTS: There were 3254 respondents (93.6% response rate); of these 17.5% (n = 570) transferred to another treatment center, 8.6% (n = 280) died, 29.2% (n = 950) defaulted, and 7.6% (n = 247) were terminated for various reasons. Hence, 1233 (37%) respondents' baseline and follow-up data were further analyzed. Respondents had a mean age of 39.2 years old and were mainly male, Malay, Muslim, married (51.1%, n = 617), and currently employed. Few showed viral seroconversion after they started MMT (HIV: 0.5%, n = 6; Hepatitis B: 0.3%, n = 4; Hepatitis C: 2.7%, n = 29). There were significant reductions in opioid use, HIV risk-taking score (p < 0.01), social functioning (p < 0.01), crime (p < 0.01), and health (p < 0.01). However, there were significant improvements in quality of life in the physical, psychological, social, and environmental domains. Factors associated with change were being married, employed, consuming alcohol, and high criminality at baseline. Lower methadone dosage was significantly associated with improvements in the physical, psychological, and environmental domains. Conclusion/Importance: The MMT program was found to be successful; hence, it should be expanded.
AD - a Masjid Tanah Health Clinic , Masjid Tanah , Melaka , Malaysia.; b Department of Psychiatry & Mental Health , Kuala Lumpur Hospital , Malaysia.; c Batu 9 Health Clinic , Selangor , Malaysia.; d Department of Psychiatry & Mental Health , Kajang Hospital , Selangor , Malaysia.; e Department of Psychiatry & Mental Health , Tuanku Ampuan Rahimah Hospital , Selangor , Malaysia.; f Jelapang Health Clinic , Perak , Malaysia.; g Sg Buloh Health Clinic , Selangor , Malaysia.; h Department of Psychological Medicine , University of Malaya Center for Addiction Sciences (UMCAS), Faculty of Medicine, University of Malaya , Kuala Lumpur , Selangor , Malaysia.; i Academic Development Centre (Adec) , University of Malaya , Kuala Lumpur , Selangor , Malaysia.
BT - Substance use & misuse
C5 - Opioids & Substance Use
CP - 2
CY - England
DO - 10.1080/10826084.2017.1385630
IS - 2
JF - Substance use & misuse
M1 - Journal Article
N2 - BACKGROUND: Opioid misuse and dependence is a global issue with a huge negative impact. In Malaysia, heroin is still the main illicit drug used, and methadone maintenance treatment (MMT) has been used since 2005. OBJECTIVE: To evaluate the effectiveness of MMT. METHODS: This was a cross-sectional study conducted in 103 treatment centers between October and December 2014 using a set of standard questionnaires. Data were analyzed using SPSS Statistics 20. RESULTS: There were 3254 respondents (93.6% response rate); of these 17.5% (n = 570) transferred to another treatment center, 8.6% (n = 280) died, 29.2% (n = 950) defaulted, and 7.6% (n = 247) were terminated for various reasons. Hence, 1233 (37%) respondents' baseline and follow-up data were further analyzed. Respondents had a mean age of 39.2 years old and were mainly male, Malay, Muslim, married (51.1%, n = 617), and currently employed. Few showed viral seroconversion after they started MMT (HIV: 0.5%, n = 6; Hepatitis B: 0.3%, n = 4; Hepatitis C: 2.7%, n = 29). There were significant reductions in opioid use, HIV risk-taking score (p < 0.01), social functioning (p < 0.01), crime (p < 0.01), and health (p < 0.01). However, there were significant improvements in quality of life in the physical, psychological, social, and environmental domains. Factors associated with change were being married, employed, consuming alcohol, and high criminality at baseline. Lower methadone dosage was significantly associated with improvements in the physical, psychological, and environmental domains. Conclusion/Importance: The MMT program was found to be successful; hence, it should be expanded.
PP - England
PY - 2018
SN - 1532-2491; 1082-6084
SP - 239
EP - 248
EP - 
T1 - Evaluation of Methadone Treatment in Malaysia: Findings from the Malaysian Methadone Treatment Outcome Study (MyTOS)
T2 - Substance use & misuse
TI - Evaluation of Methadone Treatment in Malaysia: Findings from the Malaysian Methadone Treatment Outcome Study (MyTOS)
U1 - Opioids & Substance Use
U2 - 29116878
U3 - 10.1080/10826084.2017.1385630
VL - 53
VO - 1532-2491; 1082-6084
Y1 - 2018
Y2 - Jan 28
ER -