TY - JOUR AU - C. M. Jones AU - E. B. Einstein AU - W. M. Compton A1 - AB - Drug overdose deaths are at unprecedented levels in the United States. Prescription opioids have been the most common drug involved in overdose deaths, but heroin and synthetic opioids (primarily illicit fentanyl) are increasingly implicated in overdoses. In addition, synthetic opioids are increasingly found in illicit drug supplies of heroin, cocaine, methamphetamine, and counterfeit pills. To date, the involvement of synthetic opioids in overdose deaths involving other drugs is not well characterized, limiting the ability to implement effective clinical and public health strategies. Using 2010-2016 mortality data, we describe recent trends for synthetic opioid involvement in drug overdose deaths. BT - JAMA C5 - Opioids & Substance Use CP - 17 DO - 10.1001/jama.2018.2844 IS - 17 JF - JAMA N2 - Drug overdose deaths are at unprecedented levels in the United States. Prescription opioids have been the most common drug involved in overdose deaths, but heroin and synthetic opioids (primarily illicit fentanyl) are increasingly implicated in overdoses. In addition, synthetic opioids are increasingly found in illicit drug supplies of heroin, cocaine, methamphetamine, and counterfeit pills. To date, the involvement of synthetic opioids in overdose deaths involving other drugs is not well characterized, limiting the ability to implement effective clinical and public health strategies. Using 2010-2016 mortality data, we describe recent trends for synthetic opioid involvement in drug overdose deaths. PY - 2018 SP - 1819 EP - 1821 EP - T1 - Changes in Synthetic Opioid Involvement in Drug Overdose Deaths in the United States, 2010-2016 T2 - JAMA TI - Changes in Synthetic Opioid Involvement in Drug Overdose Deaths in the United States, 2010-2016 U1 - Opioids & Substance Use U2 - 29715347 U3 - 10.1001/jama.2018.2844 VL - 319 Y1 - 2018 ER -