TY - JOUR
KW - Adolescent
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Amitriptyline/therapeutic use
KW - Antidepressive Agents, Tricyclic/therapeutic use
KW - Antidepressive Agents/therapeutic use
KW - Cognitive Therapy/methods
KW - Counseling
KW - Depressive Disorder, Major/drug therapy/psychology/therapy
KW - Family Practice/statistics & numerical data
KW - Female
KW - Fluvoxamine/therapeutic use
KW - Humans
KW - Male
KW - Middle Aged
KW - Primary Health Care/statistics & numerical data
KW - Psychotherapy, Brief/methods
KW - Psychotherapy/methods
KW - Randomized Controlled Trials as Topic/statistics & numerical data
KW - Serotonin Uptake Inhibitors/therapeutic use
KW - Therapy, Computer-Assisted/methods
KW - Treatment Outcome
AU - B. Bortolotti
AU - M. Menchetti
AU - F. Bellini
AU - M. B. Montaguti
AU - D. Berardi
A1 - 
AB - OBJECTIVE: Various studies have tested psychological therapies in the treatment of depression in primary care. Yet, concerns over their clinical effectiveness, as compared to usual general practitioner (GP) care or treatment with antidepressants, have been raised. The present meta-analysis was aimed at assessing currently available evidence on the topic. METHOD: A systematic search of electronic databases identified 10 randomized controlled trials comparing psychological forms of intervention with either usual GP care or antidepressant medication for major depression. Meta-analytical procedures were used to examine the impact of psychological intervention in primary care on depression, as compared to usual GP care and antidepressant treatment. RESULTS: The main analyses showed greater effectiveness of psychological intervention over usual GP care in both the short term [standardized mean difference (SMD)=-0.42, 95% confidence interval (CI)=-0.59 to -0.26, n=408] and long term (SMD=-0.30, 95% CI=-0.45 to -0.14, n=433). The heterogeneity test was not significant in the short term at the P<.05 level (df=5, P=.57, I(2)=0%), but it was significant in the long term (df=5, P=.004, I(2)=70.9%). The comparison between psychological forms of intervention and antidepressant medication yielded no effectiveness differences, for either the short term or the long term. CONCLUSIONS: Psychological forms of intervention are significantly linked to clinical improvement in depressive symptomatology and may be useful for supplementing usual GP care.
BT - General hospital psychiatry
C5 - HIT & Telehealth
CP - 4
CY - United States
DO - 10.1016/j.genhosppsych.2008.04.001
IS - 4
JF - General hospital psychiatry
N2 - OBJECTIVE: Various studies have tested psychological therapies in the treatment of depression in primary care. Yet, concerns over their clinical effectiveness, as compared to usual general practitioner (GP) care or treatment with antidepressants, have been raised. The present meta-analysis was aimed at assessing currently available evidence on the topic. METHOD: A systematic search of electronic databases identified 10 randomized controlled trials comparing psychological forms of intervention with either usual GP care or antidepressant medication for major depression. Meta-analytical procedures were used to examine the impact of psychological intervention in primary care on depression, as compared to usual GP care and antidepressant treatment. RESULTS: The main analyses showed greater effectiveness of psychological intervention over usual GP care in both the short term [standardized mean difference (SMD)=-0.42, 95% confidence interval (CI)=-0.59 to -0.26, n=408] and long term (SMD=-0.30, 95% CI=-0.45 to -0.14, n=433). The heterogeneity test was not significant in the short term at the P<.05 level (df=5, P=.57, I(2)=0%), but it was significant in the long term (df=5, P=.004, I(2)=70.9%). The comparison between psychological forms of intervention and antidepressant medication yielded no effectiveness differences, for either the short term or the long term. CONCLUSIONS: Psychological forms of intervention are significantly linked to clinical improvement in depressive symptomatology and may be useful for supplementing usual GP care.
PP - United States
PY - 2008
SN - 0163-8343; 0163-8343
SP - 293
EP - 302
EP - 
T1 - Psychological interventions for major depression in primary care: a meta-analytic review of randomized controlled trials
T2 - General hospital psychiatry
TI - Psychological interventions for major depression in primary care: a meta-analytic review of randomized controlled trials
U1 - HIT & Telehealth
U3 - 10.1016/j.genhosppsych.2008.04.001
VL - 30
VO - 0163-8343; 0163-8343
Y1 - 2008
ER -