TY - JOUR KW - Antidepressive Agents -- therapeutic use KW - Antipsychotic Agents -- therapeutic use KW - Comorbidity KW - Depressive Disorder, Major -- drug therapy KW - Depressive Disorder, Major -- epidemiology KW - Depressive Disorder, Major -- therapy KW - Diabetes Mellitus -- epidemiology KW - Drug Resistance KW - Electric Stimulation Therapy -- methods KW - Heart Diseases -- epidemiology KW - Hospitalization -- statistics & numerical data KW - Humans KW - Primary Health Care -- methods KW - Pulmonary Disease, Chronic Obstructive -- epidemiology KW - Quality of Life KW - Risk Factors AU - L. Culpepper A1 - C5 - Medical Home CY - United States PP - United States PY - 2010 SN - 0160-6689 (Print); 1555-2101 (Electronic) SP - 4 EP - 9 EP - T1 - Why do you need to move beyond first-line therapy for major depression? TI - Why do you need to move beyond first-line therapy for major depression? U1 - Medical Home U2 - 20977873 VL - 71 Suppl 1 VO - 0160-6689 (Print); 1555-2101 (Electronic) Y1 - 2010 ER -