TY - JOUR
AU - M. A. Morgan
AU - M. J. Coates
AU - J. A. Dunbar
AU - P. Reddy
AU - K. Schlicht
AU - J. Fuller
A1 - 
AB - OBJECTIVES: To determine the effectiveness of collaborative care in reducing depression in primary care patients with diabetes or heart disease using practice nurses as case managers. DESIGN: A two-arm open randomised cluster trial with wait-list control for 6 months. The intervention was followed over 12 months. SETTING: Eleven Australian general practices, five randomly allocated to the intervention and six to the control. PARTICIPANTS: 400 primary care patients (206 intervention, 194 control) with depression and type 2 diabetes, coronary heart disease or both. INTERVENTION: The practice nurse acted as a case manager identifying depression, reviewing pathology results, lifestyle risk factors and patient goals and priorities. Usual care continued in the controls. MAIN OUTCOME MEASURE: A five-point reduction in depression scores for patients with moderate-to-severe depression. Secondary outcome was improvements in physiological measures. RESULTS: Mean depression scores after 6 months of intervention for patients with moderate-to-severe depression decreased by 5.7+/-1.3 compared with 4.3+/-1.2 in control, a significant (p=0.012) difference. (The plus-minus is the 95% confidence range.) Intervention practices demonstrated adherence to treatment guidelines and intensification of treatment for depression, where exercise increased by 19%, referrals to exercise programmes by 16%, referrals to mental health workers (MHWs) by 7% and visits to MHWs by 17%. Control-practice exercise did not change, whereas referrals to exercise programmes dropped by 5% and visits to MHWs by 3%. Only referrals to MHW increased by 12%. Intervention improvements were sustained over 12 months, with a significant (p=0.015) decrease in 10-year cardiovascular disease risk from 27.4+/-3.4% to 24.8+/-3.8%. A review of patients indicated that the study's safety protocols were followed. CONCLUSIONS: TrueBlue participants showed significantly improved depression and treatment intensification, sustained over 12 months of intervention and reduced 10-year cardiovascular disease risk. Collaborative care using practice nurses appears to be an effective primary care intervention. TRIAL REGISTRATION: ACTRN12609000333213 (Australia and New Zealand Clinical Trials Registry).
BT - BMJ open
C5 - Education & Workforce
CP - 1
CY - England
DO - 10.1136/bmjopen-2012-002171
IS - 1
JF - BMJ open
N2 - OBJECTIVES: To determine the effectiveness of collaborative care in reducing depression in primary care patients with diabetes or heart disease using practice nurses as case managers. DESIGN: A two-arm open randomised cluster trial with wait-list control for 6 months. The intervention was followed over 12 months. SETTING: Eleven Australian general practices, five randomly allocated to the intervention and six to the control. PARTICIPANTS: 400 primary care patients (206 intervention, 194 control) with depression and type 2 diabetes, coronary heart disease or both. INTERVENTION: The practice nurse acted as a case manager identifying depression, reviewing pathology results, lifestyle risk factors and patient goals and priorities. Usual care continued in the controls. MAIN OUTCOME MEASURE: A five-point reduction in depression scores for patients with moderate-to-severe depression. Secondary outcome was improvements in physiological measures. RESULTS: Mean depression scores after 6 months of intervention for patients with moderate-to-severe depression decreased by 5.7+/-1.3 compared with 4.3+/-1.2 in control, a significant (p=0.012) difference. (The plus-minus is the 95% confidence range.) Intervention practices demonstrated adherence to treatment guidelines and intensification of treatment for depression, where exercise increased by 19%, referrals to exercise programmes by 16%, referrals to mental health workers (MHWs) by 7% and visits to MHWs by 17%. Control-practice exercise did not change, whereas referrals to exercise programmes dropped by 5% and visits to MHWs by 3%. Only referrals to MHW increased by 12%. Intervention improvements were sustained over 12 months, with a significant (p=0.015) decrease in 10-year cardiovascular disease risk from 27.4+/-3.4% to 24.8+/-3.8%. A review of patients indicated that the study's safety protocols were followed. CONCLUSIONS: TrueBlue participants showed significantly improved depression and treatment intensification, sustained over 12 months of intervention and reduced 10-year cardiovascular disease risk. Collaborative care using practice nurses appears to be an effective primary care intervention. TRIAL REGISTRATION: ACTRN12609000333213 (Australia and New Zealand Clinical Trials Registry).
PP - England
PY - 2013
SN - 2044-6055
T1 - The TrueBlue model of collaborative care using practice nurses as case managers for depression alongside diabetes or heart disease: a randomised trial
T2 - BMJ open
TI - The TrueBlue model of collaborative care using practice nurses as case managers for depression alongside diabetes or heart disease: a randomised trial
U1 - Education & Workforce
U2 - 23355671
U3 - 10.1136/bmjopen-2012-002171
VL - 3
VO - 2044-6055
Y1 - 2013
ER -