TY - JOUR KW - Adolescent KW - Alcohol-Related Disorders/drug therapy/epidemiology KW - Analgesics, Opioid/administration & dosage/adverse effects/therapeutic use KW - Buprenorphine/administration & dosage/therapeutic use KW - Child KW - Comorbidity KW - Delivery, Obstetric/methods KW - Female KW - Humans KW - Infant, Newborn KW - Methadone/administration & dosage/therapeutic use KW - Neonatal Abstinence Syndrome/drug therapy/prevention & control KW - Opiate Substitution Treatment/methods KW - Opioid-Related Disorders/diagnosis/drug therapy/epidemiology KW - Pain Management/methods KW - Pregnancy KW - Pregnancy Complications/diagnosis/drug therapy/epidemiology KW - Prenatal Care/methods/organization & administration KW - Prenatal Exposure Delayed Effects KW - Prescription Drugs/adverse effects KW - Self Medication KW - Substance Withdrawal Syndrome/prevention & control KW - United States/epidemiology AU - J. L. Young AU - P. R. Martin A1 - AB - Opioid dependence in the setting of pregnancy provides a distinct set of challenges for providers. Treatment plans must take into consideration psychiatric and medical comorbidities while balancing risks and benefits for the maternal-fetal dyad. Treatment is best offered through a comprehensive treatment program designed to effectively deliver opioid agonist maintenance treatment along with psychosocial and obstetric care. As misuse of prescription analgesics increases in the United States, identification of the problem in pregnancy will become more important because this misuse is expected to lead to an increased prevalence of opioid dependence in pregnancy. Buprenorphine as maintenance treatment of opioid dependence during pregnancy has promise and may offer some benefits, but more research is needed, especially regarding induction of actively addicted women during pregnancy. For the present, methadone maintenance remains the standard of care for agonist treatment of opioid dependence in pregnancy against which other treatments must be compared. BT - The Psychiatric clinics of North America C5 - Opioids & Substance Use CP - 2 CY - United States DO - 10.1016/j.psc.2012.03.008 IS - 2 JF - The Psychiatric clinics of North America N2 - Opioid dependence in the setting of pregnancy provides a distinct set of challenges for providers. Treatment plans must take into consideration psychiatric and medical comorbidities while balancing risks and benefits for the maternal-fetal dyad. Treatment is best offered through a comprehensive treatment program designed to effectively deliver opioid agonist maintenance treatment along with psychosocial and obstetric care. As misuse of prescription analgesics increases in the United States, identification of the problem in pregnancy will become more important because this misuse is expected to lead to an increased prevalence of opioid dependence in pregnancy. Buprenorphine as maintenance treatment of opioid dependence during pregnancy has promise and may offer some benefits, but more research is needed, especially regarding induction of actively addicted women during pregnancy. For the present, methadone maintenance remains the standard of care for agonist treatment of opioid dependence in pregnancy against which other treatments must be compared. PP - United States PY - 2012 SN - 1558-3147; 0193-953X SP - 441 EP - 460 EP - T1 - Treatment of opioid dependence in the setting of pregnancy T2 - The Psychiatric clinics of North America TI - Treatment of opioid dependence in the setting of pregnancy U1 - Opioids & Substance Use U2 - 22640765 U3 - 10.1016/j.psc.2012.03.008 VL - 35 VO - 1558-3147; 0193-953X Y1 - 2012 ER -