TY - JOUR
KW - Cancer
KW - Depression
KW - Distress
KW - psychosocial
KW - training
KW - treatment
AU - J. Turner
AU - B. Kelly
AU - D. Clarke
AU - P. Yates
AU - S. Aranda
AU - D. Jolley
AU - A. Forbes
AU - S. Chambers
AU - M. Hargraves
AU - L. Mackenzie
A1 - 
AB - PURPOSE: A stepped-wedge cluster-randomised controlled trial was conducted to evaluate the feasibility and effectiveness of a brief psychosocial intervention for depressed cancer patients, delivered by trained front-line health professionals in routine clinical care. METHODS: Nine hundred two patients were assessed across four treatment centres which were allocated in random order from control epoch to intervention epoch. Eligible patients had Hospital Anxiety and Depression Scale (HADS) scores of 8 or greater. Of eligible patients, 222 were recruited in control epoch and 247 in intervention epoch. Twenty-seven health professionals (HPs) were trained to deliver the psychosocial intervention consisting of up to four sessions, tailored to patient symptoms and distress. HPs participated in group supervision with a psychiatrist. The primary outcome, analysed by intention to treat, was depression measured with the HADS at 10 weeks after receiving the intervention. RESULTS: At 10-week follow-up, there were no significant differences in HADS score for the 181 patients in control epoch and 177 in intervention epoch (adjusted difference -1.23, 95 % CI -3.81--1.35, p = 0.35). Patients with disease progression who received the intervention experienced significant benefits in unmet practical support needs including care and support, information, and physical and daily living. CONCLUSION: A brief psychosocial intervention delivered by front-line oncology health professionals is feasible to deliver but is insufficient as a stand-alone treatment for depression in cancer patients. Psychosocial interventions should be targeted to populations most likely to experience benefit.
BT - Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
C5 - Healthcare Disparities
CP - 1
CY - Germany
DO - 10.1007/s00520-016-3382-0
IS - 1
JF - Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
N2 - PURPOSE: A stepped-wedge cluster-randomised controlled trial was conducted to evaluate the feasibility and effectiveness of a brief psychosocial intervention for depressed cancer patients, delivered by trained front-line health professionals in routine clinical care. METHODS: Nine hundred two patients were assessed across four treatment centres which were allocated in random order from control epoch to intervention epoch. Eligible patients had Hospital Anxiety and Depression Scale (HADS) scores of 8 or greater. Of eligible patients, 222 were recruited in control epoch and 247 in intervention epoch. Twenty-seven health professionals (HPs) were trained to deliver the psychosocial intervention consisting of up to four sessions, tailored to patient symptoms and distress. HPs participated in group supervision with a psychiatrist. The primary outcome, analysed by intention to treat, was depression measured with the HADS at 10 weeks after receiving the intervention. RESULTS: At 10-week follow-up, there were no significant differences in HADS score for the 181 patients in control epoch and 177 in intervention epoch (adjusted difference -1.23, 95 % CI -3.81--1.35, p = 0.35). Patients with disease progression who received the intervention experienced significant benefits in unmet practical support needs including care and support, information, and physical and daily living. CONCLUSION: A brief psychosocial intervention delivered by front-line oncology health professionals is feasible to deliver but is insufficient as a stand-alone treatment for depression in cancer patients. Psychosocial interventions should be targeted to populations most likely to experience benefit.
PP - Germany
PY - 2017
SN - 1433-7339; 0941-4355
SP - 17
EP - 26
EP - 
T1 - A tiered multidisciplinary approach to the psychosocial care of adult cancer patients integrated into routine care: the PROMPT study (a cluster-randomised controlled trial)
T2 - Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
TI - A tiered multidisciplinary approach to the psychosocial care of adult cancer patients integrated into routine care: the PROMPT study (a cluster-randomised controlled trial)
U1 - Healthcare Disparities
U2 - 27530996
U3 - 10.1007/s00520-016-3382-0
VL - 25
VO - 1433-7339; 0941-4355
Y1 - 2017
ER -