TY - JOUR
KW - Adolescent
KW - Adult
KW - Emergency Service, Hospital/statistics & numerical data
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Prospective Studies
KW - Street Drugs/poisoning
KW - Substance Abuse Detection/methods
KW - Substance-Related Disorders/diagnosis/epidemiology
KW - United Kingdom/epidemiology
KW - Young Adult
AU - D. J. Lowe
AU - H. J. Torrance
AU - A. J. Ireland
AU - F. Bloeck
AU - R. Stevenson
A1 - 
AB - OBJECTIVE: Novel psychoactive substance (NPS) as a form of recreational drug use has become increasingly popular. There is a paucity of information with regard to the prevalence and clinical sequelae of these drugs. The aim of this study was to detect NPS in patients presenting to the emergency department with suspected toxicological ingestion. PATIENTS AND METHODS: The prospective study was performed in a large emergency department in the UK. During a 3-month period 80 patients were identified by clinicians as having potentially ingested a toxicological agent. Urine samples were analysed using liquid chromatography high-resolution mass spectrometry, and basic clinical data was gathered. RESULTS: Eighty patients with a history of illicit or recreational drug consumption had urine screenings performed. Forty-nine per cent (39) of the patients undergoing a screen had more than one illicit substance detected. Twenty per cent (16) of the patients tested positive for at least one NPS. CONCLUSION: Almost half of the presented patients revealed ingestion of multiple substances, which correlated poorly with self-reporting of patients. Developing enhanced strategies to monitor evolving drug trends is crucial to the ability of clinicians to deliver care to this challenging group of patients.
BT - European journal of emergency medicine : official journal of the European Society for Emergency Medicine
C5 - Opioids & Substance Use
CP - 2
CY - England
DO - 10.1097/MEJ.0000000000000310
IS - 2
JF - European journal of emergency medicine : official journal of the European Society for Emergency Medicine
N2 - OBJECTIVE: Novel psychoactive substance (NPS) as a form of recreational drug use has become increasingly popular. There is a paucity of information with regard to the prevalence and clinical sequelae of these drugs. The aim of this study was to detect NPS in patients presenting to the emergency department with suspected toxicological ingestion. PATIENTS AND METHODS: The prospective study was performed in a large emergency department in the UK. During a 3-month period 80 patients were identified by clinicians as having potentially ingested a toxicological agent. Urine samples were analysed using liquid chromatography high-resolution mass spectrometry, and basic clinical data was gathered. RESULTS: Eighty patients with a history of illicit or recreational drug consumption had urine screenings performed. Forty-nine per cent (39) of the patients undergoing a screen had more than one illicit substance detected. Twenty per cent (16) of the patients tested positive for at least one NPS. CONCLUSION: Almost half of the presented patients revealed ingestion of multiple substances, which correlated poorly with self-reporting of patients. Developing enhanced strategies to monitor evolving drug trends is crucial to the ability of clinicians to deliver care to this challenging group of patients.
PP - England
PY - 2017
SN - 1473-5695; 0969-9546
SP - 126
EP - 129
EP - 
T1 - SODAS: Surveillance of Drugs of Abuse Study
T2 - European journal of emergency medicine : official journal of the European Society for Emergency Medicine
TI - SODAS: Surveillance of Drugs of Abuse Study
U1 - Opioids & Substance Use
U2 - 26313317
U3 - 10.1097/MEJ.0000000000000310
VL - 24
VO - 1473-5695; 0969-9546
Y1 - 2017
ER -