TY - JOUR AU - P. Bernard AU - G. Ninot AU - G. Moullec AU - S. Guillaume AU - P. Courtet AU - X. Quantin A1 - AB - INTRODUCTION: Smoking is significantly more common among persons with major depressive disorders (MDDs). Furthermore, smokers with MDD report more difficulties when they quit smoking (greater withdrawal symptoms, higher probability of relapse). The aim of this narrative review is to describe research on exercise and depression and exercise and smoking cessation. METHODS: We have critically reviewed various smoking cessation intervention programs for depressive smokers examining (a) the protective effect of exercise against relapse for smokers with MDD and (b) the benefits of exercise for treating withdrawal symptoms. We have also reviewed the current literature investigating the mechanisms between exercise-depression and exercise-smoking. RESULTS: This review suggests that exercise may reduce depressive symptoms following cessation and provide a useful strategy for managing withdrawal symptoms in smokers with MDD. Various psychological, biological, and genetic hypotheses have been tested (e.g., distraction hypothesis, expectations hypothesis, cortisol hypothesis) and few have obtained significant results. CONCLUSIONS: It might be beneficial for health professionals to recommend physical activity and promote supervised exercise sessions for smokers with MDD during smoking cessation. Future research needs to examine relationships between exercise, smoking, and depression with transdisciplinary and ecological momentary assessment. BT - Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco C5 - General Literature DO - 10.1093/ntr/ntt042 JF - Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco N2 - INTRODUCTION: Smoking is significantly more common among persons with major depressive disorders (MDDs). Furthermore, smokers with MDD report more difficulties when they quit smoking (greater withdrawal symptoms, higher probability of relapse). The aim of this narrative review is to describe research on exercise and depression and exercise and smoking cessation. METHODS: We have critically reviewed various smoking cessation intervention programs for depressive smokers examining (a) the protective effect of exercise against relapse for smokers with MDD and (b) the benefits of exercise for treating withdrawal symptoms. We have also reviewed the current literature investigating the mechanisms between exercise-depression and exercise-smoking. RESULTS: This review suggests that exercise may reduce depressive symptoms following cessation and provide a useful strategy for managing withdrawal symptoms in smokers with MDD. Various psychological, biological, and genetic hypotheses have been tested (e.g., distraction hypothesis, expectations hypothesis, cortisol hypothesis) and few have obtained significant results. CONCLUSIONS: It might be beneficial for health professionals to recommend physical activity and promote supervised exercise sessions for smokers with MDD during smoking cessation. Future research needs to examine relationships between exercise, smoking, and depression with transdisciplinary and ecological momentary assessment. PY - 2013 SN - 1469-994X; 1462-2203 T1 - Smoking Cessation, Depression, and Exercise: Empirical Evidence, Clinical Needs, and Mechanisms T2 - Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco TI - Smoking Cessation, Depression, and Exercise: Empirical Evidence, Clinical Needs, and Mechanisms U1 - General Literature U2 - 23535556 U3 - 10.1093/ntr/ntt042 VO - 1469-994X; 1462-2203 Y1 - 2013 ER -