TY - JOUR
KW - Adult
KW - Buprenorphine/administration & dosage/therapeutic use
KW - Clinical Trials as Topic
KW - Counseling/statistics & numerical data
KW - Drug Administration Schedule
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Narcotic Antagonists/administration & dosage/therapeutic use
KW - Opioid-Related Disorders/drug therapy/rehabilitation
KW - Substance Abuse Detection
KW - Substance Abuse Treatment Centers
KW - Substance Withdrawal Syndrome/drug therapy
KW - Time Factors
KW - Treatment Outcome
AU - E. C. Katz
AU - R. P. Schwartz
AU - S. King
AU - D. A. Highfield
AU - K. E. O'Grady
AU - T. Billings
AU - D. Gandhi
AU - E. Weintraub
AU - D. Glovinsky
AU - W. Barksdale
AU - B. S. Brown
A1 - 
AB - BACKGROUND: Despite evidence supporting the efficacy of buprenorphine relative to established detoxification agents such as clonidine, little research has examined: 1) how best to implement buprenorphine detoxification in outpatient settings; and 2) whether extending the length of buprenorphine detoxification improves treatment engagement and outcomes. OBJECTIVES: The current study examined the impact on 1) successful detoxification completion; 2) transition to longer-term treatment; and 3) treatment engagement of two different length opioid detoxifications using buprenorphine. METHODS: The study compared data obtained from two consecutive studies of early treatment engagement strategies. In one study (n = 364), opioid-addicted participants entered treatment through a Brief (5-day) buprenorphine detoxification. In the other study (n = 146), participants entered treatment through an Extended (i.e., 30-day) buprenorphine detoxification. RESULTS: Results indicated a greater likelihood of successful completion and of transition among participants who received the Extended as compared to the Brief detoxification. Extended detoxification participants attended more counseling sessions and submitted fewer drug-positive urine specimens during the first 30 days of treatment, inclusive of detoxification, than did Brief detoxification participants. CONCLUSIONS: Results demonstrate that longer periods of detoxification improve participant engagement in treatment and early treatment outcomes. SCIENTIFIC SIGNIFICANCE: Current findings demonstrate the feasibility of implementing an extended buprenorphine detoxification within a community-based treatment clinic.
BT - The American Journal of Drug and Alcohol Abuse
C5 - Opioids & Substance Use
CP - 2
CY - United States
DO - 10.1080/00952990802585380
IS - 2
JF - The American Journal of Drug and Alcohol Abuse
N2 - BACKGROUND: Despite evidence supporting the efficacy of buprenorphine relative to established detoxification agents such as clonidine, little research has examined: 1) how best to implement buprenorphine detoxification in outpatient settings; and 2) whether extending the length of buprenorphine detoxification improves treatment engagement and outcomes. OBJECTIVES: The current study examined the impact on 1) successful detoxification completion; 2) transition to longer-term treatment; and 3) treatment engagement of two different length opioid detoxifications using buprenorphine. METHODS: The study compared data obtained from two consecutive studies of early treatment engagement strategies. In one study (n = 364), opioid-addicted participants entered treatment through a Brief (5-day) buprenorphine detoxification. In the other study (n = 146), participants entered treatment through an Extended (i.e., 30-day) buprenorphine detoxification. RESULTS: Results indicated a greater likelihood of successful completion and of transition among participants who received the Extended as compared to the Brief detoxification. Extended detoxification participants attended more counseling sessions and submitted fewer drug-positive urine specimens during the first 30 days of treatment, inclusive of detoxification, than did Brief detoxification participants. CONCLUSIONS: Results demonstrate that longer periods of detoxification improve participant engagement in treatment and early treatment outcomes. SCIENTIFIC SIGNIFICANCE: Current findings demonstrate the feasibility of implementing an extended buprenorphine detoxification within a community-based treatment clinic.
PP - United States
PY - 2009
SN - 1097-9891; 0095-2990
SP - 63
EP - 67
EP - 
T1 - Brief vs. extended buprenorphine detoxification in a community treatment program: engagement and short-term outcomes
T2 - The American Journal of Drug and Alcohol Abuse
TI - Brief vs. extended buprenorphine detoxification in a community treatment program: engagement and short-term outcomes
U1 - Opioids & Substance Use
U2 - 19199166
U3 - 10.1080/00952990802585380
VL - 35
VO - 1097-9891; 0095-2990
Y1 - 2009
ER -