TY - JOUR
KW - analgesia
KW - Analgesics, Opioid/adverse effects
KW - Child
KW - dependence
KW - Humans
KW - Iatrogenic Disease/epidemiology
KW - Opioid-Related Disorders/diagnosis/epidemiology/etiology/therapy
KW - Opioids
KW - sedation
KW - Substance Withdrawal Syndrome/diagnosis/epidemiology/etiology/therapy
KW - United States/epidemiology
KW - Withdrawal
AU - J. Galinkin
AU - J. L. Koh
AU - Committee on Drugs
AU - Section On Anesthesiology and Pain Medicine
A1 - 
AB - Opioids are often prescribed to children for pain relief related to procedures, acute injuries, and chronic conditions. Round-the-clock dosing of opioids can produce opioid dependence within 5 days. According to a 2001 Consensus Paper from the American Academy of Pain Medicine, American Pain Society, and American Society of Addiction Medicine, dependence is defined as "a state of adaptation that is manifested by a drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug, and/or administration of an antagonist." Although the experience of many children undergoing iatrogenically induced withdrawal may be mild or goes unreported, there is currently no guidance for recognition or management of withdrawal for this population. Guidance on this subject is available only for adults and primarily for adults with substance use disorders. The guideline will summarize existing literature and provide readers with information currently not available in any single source specific for this vulnerable pediatric population.
BT - Pediatrics
C5 - Opioids & Substance Use; Healthcare Disparities
CP - 1
CY - United States
DO - 10.1542/peds.2013-3398
IS - 1
JF - Pediatrics
N2 - Opioids are often prescribed to children for pain relief related to procedures, acute injuries, and chronic conditions. Round-the-clock dosing of opioids can produce opioid dependence within 5 days. According to a 2001 Consensus Paper from the American Academy of Pain Medicine, American Pain Society, and American Society of Addiction Medicine, dependence is defined as "a state of adaptation that is manifested by a drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug, and/or administration of an antagonist." Although the experience of many children undergoing iatrogenically induced withdrawal may be mild or goes unreported, there is currently no guidance for recognition or management of withdrawal for this population. Guidance on this subject is available only for adults and primarily for adults with substance use disorders. The guideline will summarize existing literature and provide readers with information currently not available in any single source specific for this vulnerable pediatric population.
PP - United States
PY - 2014
SN - 1098-4275; 0031-4005
SP - 152
EP - 155
EP - 
T1 - Recognition and management of iatrogenically induced opioid dependence and withdrawal in children
T2 - Pediatrics
TI - Recognition and management of iatrogenically induced opioid dependence and withdrawal in children
U1 - Opioids & Substance Use; Healthcare Disparities
U2 - 24379233
U3 - 10.1542/peds.2013-3398
VL - 133
VO - 1098-4275; 0031-4005
Y1 - 2014
ER -