TY - JOUR
KW - Humans
KW - Long QT Syndrome/chemically induced/diagnosis
KW - Methadone/adverse effects/therapeutic use
KW - Opiate Substitution Treatment/adverse effects
KW - Opioid-Related Disorders/drug therapy
KW - Patient Safety/standards
KW - Torsades de Pointes/prevention & control
KW - United States
KW - United States Substance Abuse and Mental Health Services Administration
AU - J. A. Martin
AU - A. Campbell
AU - T. Killip
AU - M. Kotz
AU - M. J. Krantz
AU - M. J. Kreek
AU - B. A. McCarroll
AU - D. Mehta
AU - J. T. Payte
AU - B. Stimmel
AU - T. Taylor
AU - M. C. Haigney
AU - B. B. Wilford
AU - Substance Abuse and Mental Health Services Administration
A1 - 
AB - In an effort to enhance patient safety in opioid treatment programs, the Substance Abuse and Mental Health Saervices Administration convened a multi-disciplinary Expert Panel on the Cardiac Effects of Methadone. Panel members (Appendix A) reviewed the literature, regulatory actions, professional guidances, and opioid treatment program experiences regarding adverse cardiac events associated with methadone. The Panel concluded that, to the extent possible, every opioid treatment program should have a universal Cardiac Risk Management Plan (incorporating clinical assessment, electrocardiogram assessment, risk stratification, and prevention of drug interactions) for all patients and should strongly consider patient-specific risk minimization strategies (such as careful patient monitoring, obtaining electrocardiograms as indicated by a particular patient's risk profile, and adjusting the methadone dose as needed) for patients with identified risk factors for adverse cardiac events. The Panel also suggested specific modifications to informed consent documents, patient education, staff education, and methadone protocols.
BT - Journal of addictive diseases
C5 - Education & Workforce; Key & Foundational; Opioids & Substance Use
CP - 4
CY - England
DO - 10.1080/10550887.2011.610710
IS - 4
JF - Journal of addictive diseases
N2 - In an effort to enhance patient safety in opioid treatment programs, the Substance Abuse and Mental Health Saervices Administration convened a multi-disciplinary Expert Panel on the Cardiac Effects of Methadone. Panel members (Appendix A) reviewed the literature, regulatory actions, professional guidances, and opioid treatment program experiences regarding adverse cardiac events associated with methadone. The Panel concluded that, to the extent possible, every opioid treatment program should have a universal Cardiac Risk Management Plan (incorporating clinical assessment, electrocardiogram assessment, risk stratification, and prevention of drug interactions) for all patients and should strongly consider patient-specific risk minimization strategies (such as careful patient monitoring, obtaining electrocardiograms as indicated by a particular patient's risk profile, and adjusting the methadone dose as needed) for patients with identified risk factors for adverse cardiac events. The Panel also suggested specific modifications to informed consent documents, patient education, staff education, and methadone protocols.
PP - England
PY - 2011
SN - 1545-0848; 1055-0887
SP - 283
EP - 306
EP - 
T1 - QT interval screening in methadone maintenance treatment: report of a SAMHSA expert panel
T2 - Journal of addictive diseases
TI - QT interval screening in methadone maintenance treatment: report of a SAMHSA expert panel
U1 - Education & Workforce; Key & Foundational; Opioids & Substance Use
U2 - 22026519
U3 - 10.1080/10550887.2011.610710
VL - 30
VO - 1545-0848; 1055-0887
Y1 - 2011
ER -