TY - JOUR KW - Adult KW - drop-outs KW - Female KW - Humans KW - Male KW - Opiate Substitution Treatment KW - opioid maintenance treatment KW - Opioid-Related Disorders/rehabilitation KW - Patient Discharge KW - Patient Readmission/statistics & numerical data KW - Sweden KW - Treatment Outcome KW - treatment process AU - B. Monwell AU - A. Gerdner A1 - AB - PROBLEM: Although efficacy studies of opioid maintenance treatment (OMT) have shown evidence of treatment benefits, there is still need for studies on its effectiveness in natural clinical processes. This study investigates the development in health, substance use and social conditions of those who applied for OMT, including those denied access or discharged. METHOD: First, persons assessed for admittance in 2005-2011 (n = 127) were categorized into four trajectory groups based on whether they were admitted or denied (n = 19), discharged (n = 31), readmitted (n = 21) or had been undergoing OMT without interruption (n = 56). Second, 99 of these, the analytical sample, were interviewed at follow-up using (a) the Addiction Severity Index (ASI) for seven problem-areas and housing, and (b) self-rated change in 11 problem areas. The ASI was compared to baseline interviews after 55 months (mean). Third, outcomes within groups was studied in relation to alternative interventions. RESULTS: Within the analytical sample, those denied OMT showed no improvements at group level, those discharged had some improvements, more if readmitted than if not and those with uninterrupted OMT showed the most comprehensive improvements. Those outside OMT, denied and discharged, had considerable mortality risks related to ongoing drug use, especially in lack of well-planned alternative interventions. CONCLUSION: Improvements strongly relate to access to OMT. This study underscores that access to OMT improves the situation in all areas investigated and decreases the risk for drug-related death. It underscores the importance of two major risk situations, i.e. being denied OMT and being discharged. BT - Nordic journal of psychiatry C5 - Measures; Opioids & Substance Use CP - 1 CY - England DO - 10.1080/08039488.2018.1539120 IS - 1 JF - Nordic journal of psychiatry N2 - PROBLEM: Although efficacy studies of opioid maintenance treatment (OMT) have shown evidence of treatment benefits, there is still need for studies on its effectiveness in natural clinical processes. This study investigates the development in health, substance use and social conditions of those who applied for OMT, including those denied access or discharged. METHOD: First, persons assessed for admittance in 2005-2011 (n = 127) were categorized into four trajectory groups based on whether they were admitted or denied (n = 19), discharged (n = 31), readmitted (n = 21) or had been undergoing OMT without interruption (n = 56). Second, 99 of these, the analytical sample, were interviewed at follow-up using (a) the Addiction Severity Index (ASI) for seven problem-areas and housing, and (b) self-rated change in 11 problem areas. The ASI was compared to baseline interviews after 55 months (mean). Third, outcomes within groups was studied in relation to alternative interventions. RESULTS: Within the analytical sample, those denied OMT showed no improvements at group level, those discharged had some improvements, more if readmitted than if not and those with uninterrupted OMT showed the most comprehensive improvements. Those outside OMT, denied and discharged, had considerable mortality risks related to ongoing drug use, especially in lack of well-planned alternative interventions. CONCLUSION: Improvements strongly relate to access to OMT. This study underscores that access to OMT improves the situation in all areas investigated and decreases the risk for drug-related death. It underscores the importance of two major risk situations, i.e. being denied OMT and being discharged. PP - England PY - 2019 SN - 1502-4725; 0803-9488 SP - 24 EP - 30 EP - T1 - Opioid maintenance treatment: trajectories in and out of treatment T2 - Nordic journal of psychiatry TI - Opioid maintenance treatment: trajectories in and out of treatment U1 - Measures; Opioids & Substance Use U2 - 30636473 U3 - 10.1080/08039488.2018.1539120 VL - 73 VO - 1502-4725; 0803-9488 Y1 - 2019 ER -