TY - JOUR KW - Addiction KW - Analgesics, Opioid/adverse effects/therapeutic use KW - Behavior, Addictive KW - buprenorphine KW - Buprenorphine/adverse effects/therapeutic use KW - Craving/drug effects KW - drug treatment KW - Humans KW - Medical Toxicology KW - Opiate Substitution Treatment/adverse effects/methods KW - opioid dependence KW - Opioid-Related Disorders/diagnosis/drug therapy/psychology KW - Quality of Life KW - Risk Factors KW - Substance Abuse Treatment Centers KW - Toxicology/methods KW - Treatment Outcome AU - T. J. Wiegand A1 - AB - Buprenorphine represents a safe and effective therapy for treating opioid dependence, alleviating craving and withdrawal symptoms in opioid-dependent patients. Buprenorphine has a "blocking" effect against the action of other opioids at the mu-receptor, preventing not only opioid-induced euphoria, but CNS and respiratory depressant effects as well. Buprenorphine was approved for the treatment of opioid dependence in 2002 after the passage of Drug Abuse Treatment Act 2000 (DATA 2000) which allowed clinicians to treat opioid-dependent patients with specifically named opioid agonist therapies in an office setting. Buprenorphine programs reduce the prevalence of HIV and hepatitis C and reduce criminal behaviors associated with illicit drug use. Patients stabilized on buprenorphine have increased employment, enhanced engagement with social services, and better overall health and well-being. BT - Journal of medical toxicology : official journal of the American College of Medical Toxicology C5 - Opioids & Substance Use CP - 1 CY - United States DO - 10.1007/s13181-015-0518-4 IS - 1 JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology N2 - Buprenorphine represents a safe and effective therapy for treating opioid dependence, alleviating craving and withdrawal symptoms in opioid-dependent patients. Buprenorphine has a "blocking" effect against the action of other opioids at the mu-receptor, preventing not only opioid-induced euphoria, but CNS and respiratory depressant effects as well. Buprenorphine was approved for the treatment of opioid dependence in 2002 after the passage of Drug Abuse Treatment Act 2000 (DATA 2000) which allowed clinicians to treat opioid-dependent patients with specifically named opioid agonist therapies in an office setting. Buprenorphine programs reduce the prevalence of HIV and hepatitis C and reduce criminal behaviors associated with illicit drug use. Patients stabilized on buprenorphine have increased employment, enhanced engagement with social services, and better overall health and well-being. PP - United States PY - 2016 SN - 1937-6995; 1556-9039 SP - 64 EP - 70 EP - T1 - The New Kid on the Block--Incorporating Buprenorphine into a Medical Toxicology Practice T2 - Journal of medical toxicology : official journal of the American College of Medical Toxicology TI - The New Kid on the Block--Incorporating Buprenorphine into a Medical Toxicology Practice U1 - Opioids & Substance Use U2 - 26574020 U3 - 10.1007/s13181-015-0518-4 VL - 12 VO - 1937-6995; 1556-9039 Y1 - 2016 ER -