TY - JOUR KW - alcohol and substance abuse KW - Analgesics, Opioid/administration & dosage/adverse effects/therapeutic use KW - Computer Simulation KW - Drug Overdose/etiology/mortality/prevention & control KW - dynamic modeling KW - Health Personnel/education KW - Humans KW - modeling and simulation KW - Models, Educational KW - Models, Theoretical KW - nonlinear dynamics KW - Opioid-Related Disorders/mortality/prevention & control KW - Patient Education as Topic KW - Prescription Drug Diversion/prevention & control/statistics & numerical data KW - Risk Assessment KW - substance use KW - Systems Analysis KW - systems science KW - United States/epidemiology AU - W. Wakeland AU - A. Nielsen AU - T. D. Schmidt AU - D. McCarty AU - L. R. Webster AU - J. Fitzgerald AU - J. D. Haddox A1 - AB - Three educational interventions were simulated in a system dynamics model of the medical use, trafficking, and nonmedical use of pharmaceutical opioids. The study relied on secondary data obtained in the literature for the period of 1995 to 2008 as well as expert panel recommendations regarding model parameters and structure. The behavior of the resulting systems-level model was tested for fit against reference behavior data. After the base model was tested, logic to represent three educational interventions was added and the impact of each intervention on simulated overdose deaths was evaluated over a 7-year evaluation period, 2008 to 2015. Principal findings were that a prescriber education intervention not only reduced total overdose deaths in the model but also reduced the total number of persons who receive opioid analgesic therapy, medical user education not only reduced overdose deaths among medical users but also resulted in increased deaths from nonmedical use, and a "popularity" intervention sharply reduced overdose deaths among nonmedical users while having no effect on medical use. System dynamics modeling shows promise for evaluating potential interventions to ameliorate the adverse outcomes associated with the complex system surrounding the use of opioid analgesics to treat pain. BT - Health education & behavior : the official publication of the Society for Public Health Education C5 - Opioids & Substance Use CP - 1 Suppl CY - United States DO - 10.1177/1090198113492767 IS - 1 Suppl JF - Health education & behavior : the official publication of the Society for Public Health Education N2 - Three educational interventions were simulated in a system dynamics model of the medical use, trafficking, and nonmedical use of pharmaceutical opioids. The study relied on secondary data obtained in the literature for the period of 1995 to 2008 as well as expert panel recommendations regarding model parameters and structure. The behavior of the resulting systems-level model was tested for fit against reference behavior data. After the base model was tested, logic to represent three educational interventions was added and the impact of each intervention on simulated overdose deaths was evaluated over a 7-year evaluation period, 2008 to 2015. Principal findings were that a prescriber education intervention not only reduced total overdose deaths in the model but also reduced the total number of persons who receive opioid analgesic therapy, medical user education not only reduced overdose deaths among medical users but also resulted in increased deaths from nonmedical use, and a "popularity" intervention sharply reduced overdose deaths among nonmedical users while having no effect on medical use. System dynamics modeling shows promise for evaluating potential interventions to ameliorate the adverse outcomes associated with the complex system surrounding the use of opioid analgesics to treat pain. PP - United States PY - 2013 SN - 1552-6127; 1090-1981 SP - 74S EP - 86S EP - T1 - Modeling the impact of simulated educational interventions on the use and abuse of pharmaceutical opioids in the United States: a report on initial efforts T2 - Health education & behavior : the official publication of the Society for Public Health Education TI - Modeling the impact of simulated educational interventions on the use and abuse of pharmaceutical opioids in the United States: a report on initial efforts U1 - Opioids & Substance Use U2 - 24084403 U3 - 10.1177/1090198113492767 VL - 40 VO - 1552-6127; 1090-1981 Y1 - 2013 ER -