TY - JOUR KW - Adolescent KW - Adult KW - Bipolar Disorder/diagnosis/economics/epidemiology KW - Cost Savings/statistics & numerical data KW - Decision Support Techniques KW - Depressive Disorder, Major/diagnosis/economics/epidemiology KW - Diagnostic Errors KW - Early Diagnosis KW - Female KW - Health Care Costs KW - Humans KW - Male KW - Managed Care Programs/economics KW - Mass Screening/economics/methods KW - Models, Economic KW - Monte Carlo Method KW - Primary Health Care/economics/methods/statistics & numerical data KW - Questionnaires AU - J. Menzin AU - M. Sussman AU - E. Tafesse AU - C. Duczakowski AU - P. Neumann AU - M. Friedman A1 - AB - OBJECTIVE: Unrecognized bipolar disorder in patients presenting with a major depressive episode may lead to delayed diagnosis, inappropriate treatment, and excessive costs. This study models the cost effectiveness of screening for bipolar disorder among adults presenting for the first time with symptoms of major depressive disorder. METHOD: A decision-analysis model was used to evaluate the outcomes and cost over 5 years of screening versus not screening for bipolar disorder. Screening was defined as a 1-time administration of the Mood Disorder Questionnaire at the initial visit followed by referral to a psychiatrist for patients screening positive for bipolar disorder. Health states included correctly diagnosed bipolar disorder, unrecognized bipolar disorder, and correctly diagnosed major depressive episodes. Model outcomes included rates of correct diagnosis of bipolar disorder and discounted costs (2006 US dollars) of screening and treating major depressive episodes. Literature was the primary source of data and was collected from September 2007 through March 2009. RESULTS: According to the model, 1,000 adults in a health plan with 1 million adult members annually present with symptoms of major depressive disorder. An additional 38 patients were correctly diagnosed with depression (unipolar or a major depressive episode) or bipolar disorder (440 with screening vs 402 without screening) through a 1-time screening for bipolar disorder. Estimated 5-year discounted costs per patient were $36,044 without screening and $34,107 with screening (savings of $1,937). Accordingly, total 5-year budgetary savings were estimated at $1.94 million. Results were most sensitive to difference in treatment costs for patients with recognized versus unrecognized bipolar disorder. CONCLUSION: A 1-time screening program for bipolar disorder, when patients first present with a major depressive episode, can reduce health care costs to managed-care plans. BT - The Journal of clinical psychiatry C5 - Financing & Sustainability CP - 9 CY - United States DO - 10.4088/JCP.08m04939 IS - 9 JF - The Journal of clinical psychiatry N2 - OBJECTIVE: Unrecognized bipolar disorder in patients presenting with a major depressive episode may lead to delayed diagnosis, inappropriate treatment, and excessive costs. This study models the cost effectiveness of screening for bipolar disorder among adults presenting for the first time with symptoms of major depressive disorder. METHOD: A decision-analysis model was used to evaluate the outcomes and cost over 5 years of screening versus not screening for bipolar disorder. Screening was defined as a 1-time administration of the Mood Disorder Questionnaire at the initial visit followed by referral to a psychiatrist for patients screening positive for bipolar disorder. Health states included correctly diagnosed bipolar disorder, unrecognized bipolar disorder, and correctly diagnosed major depressive episodes. Model outcomes included rates of correct diagnosis of bipolar disorder and discounted costs (2006 US dollars) of screening and treating major depressive episodes. Literature was the primary source of data and was collected from September 2007 through March 2009. RESULTS: According to the model, 1,000 adults in a health plan with 1 million adult members annually present with symptoms of major depressive disorder. An additional 38 patients were correctly diagnosed with depression (unipolar or a major depressive episode) or bipolar disorder (440 with screening vs 402 without screening) through a 1-time screening for bipolar disorder. Estimated 5-year discounted costs per patient were $36,044 without screening and $34,107 with screening (savings of $1,937). Accordingly, total 5-year budgetary savings were estimated at $1.94 million. Results were most sensitive to difference in treatment costs for patients with recognized versus unrecognized bipolar disorder. CONCLUSION: A 1-time screening program for bipolar disorder, when patients first present with a major depressive episode, can reduce health care costs to managed-care plans. PB - Physicians Postgraduate Press, Inc PP - United States PY - 2009 SN - 1555-2101; 0160-6689 SP - 1230 EP - 1236 EP - T1 - A model of the economic impact of a bipolar disorder screening program in primary care T2 - The Journal of clinical psychiatry TI - A model of the economic impact of a bipolar disorder screening program in primary care U1 - Financing & Sustainability U2 - 19689919 U3 - 10.4088/JCP.08m04939 VL - 70 VO - 1555-2101; 0160-6689 Y1 - 2009 ER -