TY - JOUR
KW - Ambulatory Care/methods
KW - Buprenorphine/therapeutic use
KW - Drug Prescriptions
KW - Humans
KW - Narcotic Antagonists/therapeutic use
KW - Opioid-Related Disorders/drug therapy
KW - Treatment Outcome
KW - United States
AU - P. A. Donaher
AU - C. Welsh
A1 - 
AB - Legislation has enabled physicians to treat opioid-dependent patients with an office-based maintenance program using buprenorphine, a partial mu-opioid receptor agonist. Clinical studies indicate buprenorphine effectively manages opioid addiction. Buprenorphine is more effective than placebo for managing opioid addiction but may not be superior to methadone if high doses are needed. It is comparable to lower doses of methadone, however. Treatment phases include induction, stabilization, and maintenance. Buprenorphine therapy should be initiated at the onset of withdrawal symptoms and adjusted to address withdrawal symptoms and cravings. Advantages of buprenorphine include low abuse potential and high availability for office use. Disadvantages include high cost and possible lack of effectiveness in patients who require high methadone doses. Most family physicians are required to complete eight hours of training before they can prescribe buprenorphine for opioid addiction.
BT - American Family Physician
C5 - Opioids & Substance Use; Healthcare Policy
CP - 9
CY - United States
IS - 9
JF - American Family Physician
N2 - Legislation has enabled physicians to treat opioid-dependent patients with an office-based maintenance program using buprenorphine, a partial mu-opioid receptor agonist. Clinical studies indicate buprenorphine effectively manages opioid addiction. Buprenorphine is more effective than placebo for managing opioid addiction but may not be superior to methadone if high doses are needed. It is comparable to lower doses of methadone, however. Treatment phases include induction, stabilization, and maintenance. Buprenorphine therapy should be initiated at the onset of withdrawal symptoms and adjusted to address withdrawal symptoms and cravings. Advantages of buprenorphine include low abuse potential and high availability for office use. Disadvantages include high cost and possible lack of effectiveness in patients who require high methadone doses. Most family physicians are required to complete eight hours of training before they can prescribe buprenorphine for opioid addiction.
PP - United States
PY - 2006
SN - 0002-838X; 0002-838X
SP - 1573
EP - 1578
EP - 
T1 - Managing opioid addiction with buprenorphine
T2 - American Family Physician
TI - Managing opioid addiction with buprenorphine
U1 - Opioids & Substance Use; Healthcare Policy
U2 - 16719249
VL - 73
VO - 0002-838X; 0002-838X
Y1 - 2006
ER -