TY - JOUR KW - Drug overdose KW - Drug Overdose/drug therapy KW - Health Services Accessibility/legislation & jurisprudence KW - Humans KW - Legal liability KW - Liability, Legal KW - naloxone KW - Naloxone/therapeutic use KW - Narcotic Antagonists/therapeutic use KW - Opioid-Related Disorders/drug therapy KW - Opioids KW - Public Health KW - United States AU - J. E. Brodrick AU - C. K. Brodrick AU - B. Adinoff A1 - AB - BACKGROUND: Since the late 1980s, opioid-related morbidity and mortality in the United States has dramatically increased. This serious epidemic requires a coordinated medical, public policy, and social response. It is becoming readily apparent that widespread provision of naloxone may help to address this problem. However, because naloxone access laws vary between states, the extent of antidote dissemination may be limited by a given provider's geographic location. OBJECTIVE: This review targets a physician or prescriber audience, in hopes of providing evidence for the safety and utility of naloxone, education on the baseline legal liability of naloxone provision and protections afforded by access laws, and resources for the proposal of statewide legislation to promote antidote distribution. CONCLUSION: Evidence suggests that naloxone administration by laypersons, pursuant to physician prescription or standing order, is safe and effective for reversal of opioid overdose. As of July 2015, 44 states and the District of Columbia have passed naloxone access laws, offering varying degrees of protections for prescribers. Although the likelihood of naloxone-related legal action may parallel that inherent to the usual practice of medicine, providers should be mindful of potential scenarios, exercise methods to mitigate risk, and appreciate the utility of comprehensive naloxone access legislation in orchestrating a coordinated response to the opioid overdose epidemic. BT - The American Journal of Drug and Alcohol Abuse C5 - Opioids & Substance Use; Education & Workforce CP - 2 CY - England DO - 10.3109/00952990.2015.1109648 IS - 2 JF - The American Journal of Drug and Alcohol Abuse N2 - BACKGROUND: Since the late 1980s, opioid-related morbidity and mortality in the United States has dramatically increased. This serious epidemic requires a coordinated medical, public policy, and social response. It is becoming readily apparent that widespread provision of naloxone may help to address this problem. However, because naloxone access laws vary between states, the extent of antidote dissemination may be limited by a given provider's geographic location. OBJECTIVE: This review targets a physician or prescriber audience, in hopes of providing evidence for the safety and utility of naloxone, education on the baseline legal liability of naloxone provision and protections afforded by access laws, and resources for the proposal of statewide legislation to promote antidote distribution. CONCLUSION: Evidence suggests that naloxone administration by laypersons, pursuant to physician prescription or standing order, is safe and effective for reversal of opioid overdose. As of July 2015, 44 states and the District of Columbia have passed naloxone access laws, offering varying degrees of protections for prescribers. Although the likelihood of naloxone-related legal action may parallel that inherent to the usual practice of medicine, providers should be mindful of potential scenarios, exercise methods to mitigate risk, and appreciate the utility of comprehensive naloxone access legislation in orchestrating a coordinated response to the opioid overdose epidemic. PP - England PY - 2016 SN - 1097-9891; 0095-2990 SP - 117 EP - 128 EP - T1 - Legal regimes surrounding naloxone access: considerations for prescribers T2 - The American Journal of Drug and Alcohol Abuse TI - Legal regimes surrounding naloxone access: considerations for prescribers U1 - Opioids & Substance Use; Education & Workforce U2 - 26809471 U3 - 10.3109/00952990.2015.1109648 VL - 42 VO - 1097-9891; 0095-2990 Y1 - 2016 ER -