TY - JOUR KW - African Americans/psychology KW - Aged KW - Antidepressive Agents/therapeutic use KW - Depression/blood/complications/drug therapy KW - Diabetes Mellitus, Type 2/blood/drug therapy/psychology KW - Female KW - Hemoglobin A, Glycosylated/metabolism KW - Humans KW - Hypoglycemic Agents/therapeutic use KW - Male KW - Middle Aged KW - Patient Compliance KW - Philadelphia KW - Pilot Projects KW - Systems Integration AU - H. R. Bogner AU - H. F. de Vries A1 - AB - PURPOSE: The purpose of this study was to examine whether integrating depression treatment into care for type 2 diabetes mellitus among older African Americans improved medication adherence, glycemic control, and depression outcomes. METHODS: Older African Americans prescribed pharmacotherapy for type 2 diabetes mellitus and depression from physicians at a large primary care practice in west Philadelphia were randomly assigned to an integrated care intervention or usual care. Adherence was assessed at baseline, 2, 4, and 6 weeks using the Medication Event Monitoring System to assess adherence. Outcomes assessed at baseline and 12 weeks included standard laboratory tests to measure glycemic control and the Center for Epidemiologic Studies Depression Scale (CES-D) to assess depression. RESULTS: In all, 58 participants aged 50 to 80 years participated. The proportion of participants who had 80% or greater adherence to an oral hypoglycemic (intervention 62.1% vs usual care 24.1%) and an antidepressant (intervention 62.1% vs usual care 10.3%) was greater in the intervention group in comparison with the usual care group at 6 weeks. Participants in the integrated care intervention had lower levels of glycosylated hemoglobin (intervention 6.7% vs usual care 7.9%) and fewer depressive symptoms (CES-D mean scores: intervention 9.6 vs usual care 16.6) compared with participants in the usual care group at 12 weeks. CONCLUSION: A pilot randomized controlled trial integrating type 2 diabetes mellitus treatment and depression was successful in improving outcomes among older African Americans. Integrated interventions may be more feasible and effective in real-world practices with competing demands for limited resources. BT - The Diabetes educator C5 - General Literature CP - 2 CY - United States DO - 10.1177/0145721709356115 IS - 2 JF - The Diabetes educator N2 - PURPOSE: The purpose of this study was to examine whether integrating depression treatment into care for type 2 diabetes mellitus among older African Americans improved medication adherence, glycemic control, and depression outcomes. METHODS: Older African Americans prescribed pharmacotherapy for type 2 diabetes mellitus and depression from physicians at a large primary care practice in west Philadelphia were randomly assigned to an integrated care intervention or usual care. Adherence was assessed at baseline, 2, 4, and 6 weeks using the Medication Event Monitoring System to assess adherence. Outcomes assessed at baseline and 12 weeks included standard laboratory tests to measure glycemic control and the Center for Epidemiologic Studies Depression Scale (CES-D) to assess depression. RESULTS: In all, 58 participants aged 50 to 80 years participated. The proportion of participants who had 80% or greater adherence to an oral hypoglycemic (intervention 62.1% vs usual care 24.1%) and an antidepressant (intervention 62.1% vs usual care 10.3%) was greater in the intervention group in comparison with the usual care group at 6 weeks. Participants in the integrated care intervention had lower levels of glycosylated hemoglobin (intervention 6.7% vs usual care 7.9%) and fewer depressive symptoms (CES-D mean scores: intervention 9.6 vs usual care 16.6) compared with participants in the usual care group at 12 weeks. CONCLUSION: A pilot randomized controlled trial integrating type 2 diabetes mellitus treatment and depression was successful in improving outcomes among older African Americans. Integrated interventions may be more feasible and effective in real-world practices with competing demands for limited resources. PP - United States PY - 2010 SN - 1554-6063; 0145-7217 SP - 284 EP - 292 EP - T1 - Integrating type 2 diabetes mellitus and depression treatment among African Americans: a randomized controlled pilot trial T2 - The Diabetes educator TI - Integrating type 2 diabetes mellitus and depression treatment among African Americans: a randomized controlled pilot trial U1 - General Literature U2 - 20040705 U3 - 10.1177/0145721709356115 VL - 36 VO - 1554-6063; 0145-7217 Y1 - 2010 ER -