TY - JOUR
AU - P. A. Pirraglia
AU - B. Casserly
AU - R. Velasco
AU - M. L. Borgia
AU - L. Nici
A1 - 
AB - OBJECTIVE: Pulmonary rehabilitation (PR) has emerged over the last decade as an essential component of an integrated approach to managing patients with chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD). We sought to examine how depression and anxiety symptom changes relate to disease-specific quality of life outcomes following PR. METHODS: We performed a cohort study of 81 patients with COPD who completed PR at a Veterans Administration Medical Center. Pulmonary rehabilitation consisted of supervised exercise training and education twice weekly for 8 weeks. Beck Depression and Anxiety Inventories (BDI and BAI) assessed symptom burden at baseline and completion of PR. We measured change in disease-specific quality of life using the dyspnea, mastery, emotion and fatigue domains of the Chronic Respiratory Questionnaire Self-Reported (CRQ-SR) from baseline to completion of PR. RESULTS: Participants were 69.8+/-9.1 years old and all male. Forced expiratory volume in 1 s (FEV1) was 1.23+/-0.39 L. The CRQ-SR scores improved significantly: dyspnea (P<.0001), mastery (P=.015) and fatigue (P=.017). The BDI scores improved significantly (13.1+/-10.5 to 10.8+/-9.9, P=.003; BAI: 13.1+/-10.1 to 12.1+/-11.7). Multivariate regression models controlling for age, FEV1, depression treatment and anxiety treatment showed that improvement in depressive symptoms were associated with improvement in fatigue (P=.003), emotion (P=.003) and mastery (P=.01). Anxiety symptom change was not significantly associated with change in disease-specific quality of life domains. CONCLUSION: Addressing anxiety symptoms in PR patients may be indicated because disease-specific quality of life improvement appears to be associated with mood.
BT - Journal of psychosomatic research
C5 - General Literature
CP - 1
CY - England
DO - 10.1016/j.jpsychores.2011.01.002
IS - 1
JF - Journal of psychosomatic research
N2 - OBJECTIVE: Pulmonary rehabilitation (PR) has emerged over the last decade as an essential component of an integrated approach to managing patients with chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD). We sought to examine how depression and anxiety symptom changes relate to disease-specific quality of life outcomes following PR. METHODS: We performed a cohort study of 81 patients with COPD who completed PR at a Veterans Administration Medical Center. Pulmonary rehabilitation consisted of supervised exercise training and education twice weekly for 8 weeks. Beck Depression and Anxiety Inventories (BDI and BAI) assessed symptom burden at baseline and completion of PR. We measured change in disease-specific quality of life using the dyspnea, mastery, emotion and fatigue domains of the Chronic Respiratory Questionnaire Self-Reported (CRQ-SR) from baseline to completion of PR. RESULTS: Participants were 69.8+/-9.1 years old and all male. Forced expiratory volume in 1 s (FEV1) was 1.23+/-0.39 L. The CRQ-SR scores improved significantly: dyspnea (P<.0001), mastery (P=.015) and fatigue (P=.017). The BDI scores improved significantly (13.1+/-10.5 to 10.8+/-9.9, P=.003; BAI: 13.1+/-10.1 to 12.1+/-11.7). Multivariate regression models controlling for age, FEV1, depression treatment and anxiety treatment showed that improvement in depressive symptoms were associated with improvement in fatigue (P=.003), emotion (P=.003) and mastery (P=.01). Anxiety symptom change was not significantly associated with change in disease-specific quality of life domains. CONCLUSION: Addressing anxiety symptoms in PR patients may be indicated because disease-specific quality of life improvement appears to be associated with mood.
PP - England
PY - 2011
SN - 1879-1360; 0022-3999
SP - 45
EP - 49
EP - 
T1 - Association of change in depression and anxiety symptoms with functional outcomes in pulmonary rehabilitation patients
T2 - Journal of psychosomatic research
TI - Association of change in depression and anxiety symptoms with functional outcomes in pulmonary rehabilitation patients
U1 - General Literature
U2 - 21665012
U3 - 10.1016/j.jpsychores.2011.01.002
VL - 71
VO - 1879-1360; 0022-3999
Y1 - 2011
ER -